1 Introduction
On this page
Ariax Bio is a shared workspace for scientists and AI agents to prepare, run, and review protein-design campaigns. Work on the website, delegate to your agent, or collaborate at any stage. Inputs, scientific settings, progress, structures, and results stay connected to the same projects.
Working with an agent? Connect it with the Ariax CLI → Bundled skills cover all five engines, campaign planning, and result interpretation. You set the scientific direction and compute scope; Ariax handles GPU provisioning and workflow execution.
Our mission is to lower the technical, logistical, and cost barriers to computational protein design for academic researchers, biotech and industry scientists, and students. Read our founding story.
1.1 Our Mission#
Open Science, No Black Boxes#
Ariax provides facile access to the latest, vetted open-source computational protein design tools, such as BindCraft, BoltzGen, and PXDesign, via a user-friendly interface. There is no secret sauce or proprietary algorithms: scientists can trust transparent, peer‑reviewed methods. We also offer an open‑source scoring option for BindCraft, FreeBindCraft, which removes Rosetta licensing requirements; see our announcement. Learn about BoltzGen in our news post: /resources/boltzgen-arrives-at-ariax-bio. Learn about PXDesign in our news post: /resources/pxdesign-miniprotein-design.
BindCraft2 extends this lineup with broader binder formats and biological objectives. Its upstream license is source-available; customers running it on Ariax pay only for compute and do not need a separate commercial license. See the BindCraft2 announcement.
Transparent, Affordable Pricing#
Pay for the GPU time your projects use, with no subscription or platform fee. Turbo scales the applicable single-GPU rate by GPU count. Check the pricing page for current rates and comparisons, or read Billing & Credits for allocation terms.
On-demand GPU Access#
Choose from GPU classes including B300, B200, H200, and H100. Ariax provisions compute for your campaign according to its workflow, GPU preferences, and available capacity. See the pricing page for the current lineup.
1.2 What You Can Do with Ariax.bio#
- Launch and manage computational protein design projects using BindCraft, BindCraft2, BoltzGen, PXDesign, or ESMFold2-pipeline
- Bring an agent into new, ongoing, or completed projects
- Visualize structures and ask your agent to analyze downloaded results
- Track project progress and resource usage
- Design across modalities: Fab, scFv, VHH nanobodies, large binders, miniproteins, Ankyrin Repeat Protein, linear and cyclic peptides, and helicons
1.3 What's in This Documentation?#
2. Getting Started
Learn how to sign up, log in, and set up your account.
3. Dashboard Overview
Understand the main dashboard, navigation, and key actions.
4. Project Types
Compare design engines and formats, including Fab, scFv, VHH, miniproteins, Ankyrin Repeat Protein, and peptides.
5. Prepare Inputs
Free browser tool for trimming PDB files, visualizing structures, and selecting hotspots.
6. BindCraft Project Setup
From PDB upload to BindCraft settings for miniprotein and peptide design.
BindCraft2 Project Setup
Choose targets and binder formats, use optional biological objectives, and review structures, CSVs, logs, and archives.
7. BoltzGen Project Setup
Configure and launch BoltzGen projects for antibodies, cyclic peptides, helicons, miniproteins, peptides, or small‑molecule targeting.
8. PXDesign Project Setup
Configure and launch PXDesign projects for diffusion-based miniprotein binder design with dual-filter ranking.
ESMFold2-pipeline Project Setup
Configure miniprotein, VHH, or scFv campaigns and review Protenix validation.
9. Project Detail Page
Status bars, logs, structure viewers, downloads.
10. Settings
Notification toggles and profile management.
11. Billing & Credits
Pricing overview, credit purchases, top-up, invoices.
12. Teams
Shared billing for research groups and collaborators.
Agent API & CLI
Connect your agent, prepare a BindCraft2 campaign, and review existing projects together.
CLI & API Reference
Commands, installation channels, recovery, downloads, feedback, and the REST API.
13. Support & Resources
FAQs, troubleshooting, and contact channels.
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